Antitumor And Antioxidant Activity Of Bidens Pilosa Against Ehrlisch Ascites Carcinoma In Rodents

Abstract

One of India's earliest medical systems, siddha, is thought to have been a major source of support for the early Tamils and Dravidians in South India. In addition to being the oldest system, it offers more specializations than Ayurvedic methods. The edible herb Bidens pilosa L. has been used traditionally for a number of medical conditions in many different countries. The herbaceous plant Bidens pilosa L. (Asteraceae, Heliantheae) is widely distributed throughout Africa, America, China, and Japan. Despite being indigenous to South America, Bidens pilosa L. is now found all over the world, particularly in tropical and subtropical regions. B. pilosa is a widely available herb that is easy to grow. It is acknowledged as an important dietary supplement with therapeutic advantages for both people and animals. According to reports, B. pilosa contains active chemicals with more than 40 distinct bioactivities. The current laboratory research attempts to identify the active ingredients that mediate these antioxidant and anticancer properties and explore their underlying mechanisms. These elements support the antioxidant and anticancer effects of Bidens pilosa. According to this study, Bidens pilosa extended the survival of mice with EAC tumors by lowering lipid peroxidation and raising the liver's natural levels of antioxidant enzymes. Additionally, phenols, flavonoids, and tannins have been found through phytochemical studies. These substances are well known for their antioxidant qualities, which can reduce oxidative stress and inflammation in addition to other health advantages. To completely comprehend their modes of action and possible therapeutic uses, more investigation is required.