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Wilms’ tumor is a type of childhood cancer that starts in the kidneys. It is the most common type of kidney cancer in children. About 9 of 10 kidney cancers in children are Wilms tumors. Cancer starts when cells in the body begin to grow out of control. Cells in nearly any part of the body can become cancer. Most Wilms tumors or unilateral, which means they affect only one kidney. Most often there is only one tumor, but a small number of children with tumors have more than one tumor in the same kidney. About 5% to 10% of children with Wilms tumors have bilateral disease (tumors in both Kidneys). Wilms tumor often become quite large before they are noticed. The average newly found Wilms tumor is many times larger than the kidney in which it started. Most Wilms tumors are found before they have spread (metastasized) to other organs. Other type of kidney cancers in children are Mesoblastic nephroma, Clear cell sarcoma of kidney (CCSK), malignant rhabdoid tumor of the kidney, renal cell carcinoma.


Wilms tumor, pathology, genetics, management

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